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NSAIDs May Prevent Stomach Cancer, Especially in H. Pylori-Infected Individuals with Gastric Ulcers
Posted: Tuesday, 15 June 2010 12:01 AM
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In a recent study, published online in the May
Journal of Clinical Oncology
, researchers looked at NSAID (Non-Steroidal Anti-Inflammatory Drugs) use as a method to prevent gastric cancer in patients with gastric ulcers. The study principally focused on subjects who were H. pylori infected.
In a recent study, published online in the May
Journal of Clinical Oncology
, researchers looked at NSAID (Non-Steroidal Anti-Inflammatory Drugs) use as a method to prevent gastric cancer in patients with gastric ulcers. The study principally focused on subjects who were H. pylori infected.
Data from the Taiwan National Health Insurance Database, containing information from more than 50,000 patients diagnosed with peptic ulcer disease, was evaluated.
Findings show that patients with gastric ulcers who used NSAIDs had a lower risk of developing gastric cancer when compared to the general population. More interesting is that an even lower risk of
gastric cancer
was present in the patients with gastric ulcers who were H. pylori positive.
While NSAIDs seem to offer protection against cancer in patients with gastric ulcer, they do not protect patients with duodenal ulcer.
The study concluded that regular use of NSAIDs may be an effective tool in preventing stomach cancer in H. pylori-infected patients with gastric ulcers.
Gastric cancer has been linked to infection with
Helicobacter pylori
, a bacteria responsible for ulcers and a variety of other medical conditions. Several methods exist for detecting H. pylori including
urea breath tests
.
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